Logistic regression models of the association between H. pylori infection, serum pepsinogen levels and vibriocidal seroconversion after immunization with a single oral dose of CVD 103-HgR.

Partially adjusted analysis, in addition to H. pylori serostatus/PG levels, age and sex were added to the analysis.The following variables were entered: H. pylori infection, age (in years as a continuous variable), sex, PG I, PG II, PG I∶PG II ratio, baseline vibriocidal antibody titers (transformed into natural logarithm) S. flexneri 2a IgG and hepatitis A antibodies (as markers for environmental fecal contamination and low socioeconomic status). The final model of children aged S. flexneri antibodies but it was not significantly associated with vibriocidal seroconversion.In addition to H. pylori/PG II status, the following variables were entered to the analysis: age (in years as a continuous variable), gender, S. flexneri 2a IgG, hepatitis A antibodies and baseline vibriocidal antibody titers. The final model included the variables gender and hepatitis A, but they were not significantly associated with vibriocidal antibody seroconversion,