five

TCR usage by antigen-inexperienced memory-like cells

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA633838
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We compared TCR repertoires used by naive and antigen-inexperienced memory-like CD8+ T cells (aka virtual memory T cells) in young and aged C57BL/6 mice. The goal of this study was to address the hypothesis that naive and antigen-inexperienced memory-like T cells have differential TCR usage in young and aged animals. Our data revealed that antigen-inexperienced memory-like T cells originate from identical T-cell clones in young and aged mice.
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2020-05-19
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