The short time-series transcriptome profiles of a human adipose mesenchymal stem cell by electrical stimulation of enzymatic biofuel cell
收藏干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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We investigate the mRNA expression properties of hAD-MSCs by electrical stimulation using EBFC as an electrical regulator. We set up three different electrical currents, at 120±10.2, 250±11.5, and 500±16.2 nA/cm2 in hAD-MSCs. We performed transcriptome profiling to analyze the impact of EBFC-derived electrical current on gene expression using next-generation sequencing (NGS).Among the 166 up-regulated genes, 98 genes were significantly enriched into the UniProtKB functional categories such as ribosomal protein, alternative splicing, ribonucleoprotein, and amino-acid biosynthesis. This indicate that the genes highly associated with metabolic regulation of cell growth and proliferation have been changed by electrical stimulation in the EBFCs.
提供机构：
CHA University
创建时间：
2022-02-20
