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HDAC1/2 -mediated repression of Wnt receptors controls polarity orientation in epidermal stem cells in C. elegans.

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NIAID Data Ecosystem2026-05-10 收录
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In this study we employ TargetedDamID to identify targets within the epidermis for the histone deacetylase HDA-1 that we identified as a key epidermal development regulator. Overall design: Identification of HDA-1 genome-wide binding by epidermis-specific expression of HDA-1:Dam fusion in C. elegans. Samples containing the NLS-GFP:dam fusion only constitute control samples.

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2026-02-23
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