Subjects' demographics, medical history, living habits, and laboratory test results.

For some categories, subjects' data were not available: 191for hypertension, 65 for diabetes mellitus, 321 for cardiovascular disease, and 491 for hyperlipidemia.Smoking index (SI) = number of cigarettes per day × years of smoking.Results for continuous variables are medians (IQR: Q1, Q3) and compared between groups by Mann-Whitney U tests. Results for categorical variables are n(%) and were compared between groups by Chi-square tests or Fisher's exact tests if any cell numbers were *indicates significantly different between case and control groups.