3´-end sequencing of poly(A)+ RNA in wild-type Saccharomyces cerevisiae and nuclear exosome mutant strains

The nuclear exosome performs critical functions in non-coding RNA processing, and in diverse surveillance functions including the quality control of mRNP formation, and in the removal of pervasive transcripts核外切体（nuclear exosome）在非编码RNA（non-coding RNA）加工过程中发挥关键功能，同时参与多种监控功能，涵盖信使核糖核蛋白颗粒（mRNP）形成的质量控制，以及普遍转录本的清除。