Co-evolving JAK2V617F+ relapsed AML and donor T cells with PD-1 blockade after stem cell transplantation: an index case [ATAC-seq]. Co-evolving JAK2V617F+ relapsed AML and donor T cells with PD-1 blockade after stem cell transplantation: an index case [ATAC-seq]
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA694429
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资源简介：
JAK2V617+ myeloproliferative disease has been reported to overexpress PD-L1 rationalizing therapeutic PD-1 blockade. We performed an integrated single cell analysis on samples from an exceptional responder to nivolumab to elucidate determinants of response in this patient. Overall design: Mononuclear cells from peripheral blood were obtained from one patient with transient response to nivolumab and sequenced using mtscATAC-seq on the 10x platform
创建时间：
2021-01-24
