In vitro antifungal activities of KR-72 combined with commercially available antifungal agents against C. neoformans.
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aKR, KR-72; FDX, Fludioxonil; 5Fc, 5-flucytosine; FCZ, fluconazole. MIC50 was determined by CLSI method. For calculation purposes, >32, >4, >2, and >0.5 were assumed to be 32, 4, 2, and 0.5. For all checkerboard assays, C. neoformans H99 strain was used.bFICI≤0.5 = synergy, FICI>4.0 = antagonism, 0.5[38].In vitro antifungal activities of KR-72 combined with commercially available antifungal agents against C. neoformans.
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2015-12-02
