The accuracy of one to six Kato-Katzs and one point-of-care circulating cathodic antigen test for diagnosing S. mansoni infections.

One to six Kato-Katz thick smears (Kato-Katzs) and a single point-of-care circulating cathodic antigen test (POC-CCA) (comparing if trace readings are counted as positive (POC-CCA-t+) or negative (POC-CCA-t−)) for detecting S. mansoni infections in primary-school children in Mayuge District, Uganda, comparing with either a ‘gold standard’ of six Kato-Katzs (upper half of the table) or with both six Kato-Katzs and one POC-CCA (lower half of the table) for diagnosis. Sample sizes are included in the timeline on the top row, with prevalence (as measured by the respective ‘gold standard’) and intensity from six Kato-Katzs. NB prevalence and mean infection intensities differ from Table 2 and Figures 4A and 5 as these, here, are calculated from individuals with six Kato-Katzs and POC-CCA results (n = 367), rather than just six Kato-Katzs (n = 1065) (Figure 1). 95% confidence intervals are shown in parentheses. Prev = prevalence, Sens = sensitivity, Spec = specificity, NPV = negative predictive value, PPV = positive predictive value.The accuracy of one to six Kato-Katzs and one point-of-care circulating cathodic antigen test for diagnosing S. mansoni infections.