Dataset related to the article "Valve type and post-dilation impact on transprosthetic gradients in patients undergoing transcatheter aortic Valve-in-Valve procedure"

This record contains partial raw data related to the article "Valve type and post-dilation impact on transprosthetic gradients in patients undergoing transcatheter aortic Valve-in-Valve procedure" Aims: Valve-in-Valve transcatheter aortic valve replacement (ViV-TAVR) is an appealing treatment option for patients with degenerated aortic bioprosthetic valves. However, higher post-procedural transprosthetic gradients are more common after ViV-TAVR than after TAVR for native aortic valve stenosis. We sought to evaluate the impact of type of implanted valve and balloon post-dilation on echocardiographic results and mortality in ViV-TAVR patients. Methods and Results: One hundred-eleven consecutive patients were enrolled. A balloon-expandable valve, a self-expandable valve without balloon post-dilation, and a self-expandable valve with balloon post-dilation were performed in 35 (Group 1), 39 (Group 2), and 37 (Group 3) patients, respectively. All patients underwent comprehensive transthoracic echocardiography at baseline, discharge, and 6-12 months follow-up. Successful ViV-TAVR was performed in 110 patients (99%). Baseline transprosthetic gradients, left ventricular volumes, ejection fraction, and pulmonary artery systolic pressure were similar among groups. All groups experienced a significant reduction in postprocedural gradients at discharge and during the 6-12 months follow-up compared to baseline. At discharge, the lowest mean gradient was observed in Group 3 (12±7 mmHg) compared to both Group 1 (20±9 mmHg) and Group 2 (17±8 mmHg, p=0.001). This result was confirmed at 6-12 months follow-up (p=0.012). Similar 5-year all-cause mortality was observed among groups (34%, 36%, 14%, respectively, p=0.056). Conclusions: In patients with failed surgical aortic prosthesis, ViV-TAVR is an effective treatment option associated with sustained improved hemodynamics regardless of transcatheter valve type and use of balloon post-dilation. However, self-expandable valves with balloon post-dilation showed lower transprosthetic gradients.