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Arachidonate is oxidised to 15R-HETE by Acetyl-PTGS2

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reactome.org2025-01-15 收录
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Aspirin acetylates the cyclooxygenase, prostaglandin G/H synthase 2 (PTGS2) aka COX2. The acetylated PTGS2 triggers the formation of 15R-hydroxyeicosatetraenoate (15R-HETE) from arachidonate (Claria & Serhan 1995).

阿司匹林通过乙酰化环氧化酶,前列腺素G/H合酶2(PTGS2),亦称COX2,从而触发15R-羟基二十碳四烯酸(15R-HETE)从花生四烯酸(Claria & Serhan 1995)的生成。
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