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The Immunologic Effects of Mesalamine in Treated HIV-Infected Individuals with Incomplete CD4+ T Cell Recovery: A Randomized Crossover Trial

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Figshare2016-01-15 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_The_Immunologic_Effects_of_Mesalamine_in_Treated_HIV_Infected_Individuals_with_Incomplete_CD4_T_Cell_Recovery_A_Randomized_Crossover_Trial_/1323613
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The anti-inflammatory agent, mesalamine (5-aminosalicylic acid) has been shown to decrease mucosal inflammation in ulcerative colitis. The effect of mesalamine in HIV-infected individuals, who exhibit abnormal mucosal immune activation and microbial translocation (MT), has not been established in a placebo-controlled trial. We randomized 33 HIV-infected subjects with CD4 counts 3 and plasma HIV RNA levels Trial RegistrationClinicalTrials.gov NCT01090102
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2016-01-15
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