Crystal structure of the human OX2R bound to the insomnia drug lemborexant.
收藏Protein Data Bank Japan2024-11-06 更新2026-04-19 收录
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Crystal structure of the human OX2R bound to the insomnia drug lemborexant. Descriptor: (1~{R},2~{S})-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-~{N}-(5-fluoranylpyridin-2-yl)-2-(3-fluorophenyl)cyclopropane-1-carboxamide, Orexin receptor type 2 Authors: Asada, H, Im, D, Iwata, S. Deposit date: 2022-05-11 Release date: 2022-11-23 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor. Structure, 30, 2022
创建时间:
2022-05-11



