Systems biology of ferroptosis: a modeling approach (source code)
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资源简介：
Source code to reproduce figures in
A. Konstorum, L. Tesfay and B.T. Paul et al., Systems biology of ferroptosis: a modeling approach, Journal of Theoretical Biology, https://doi.org/10.1016/j.jtbi.2020.110222
Software necessary for the code: Matlab
Contact: Anna Konstorum (konstorum@uchc.edu)
Instructions to reproduce select figures (code below can be modified to reproduce the remaining simulation figures):
Figure 2:
Panel (a)
>>Ferroptosis_model(40,2,0,0);
Panel (b)
+ Erastin: >>Ferroptosis_model(40,2,2,0);
+ RSL3: >>Ferroptosis_model(40,2,0,2);
Figure 3:
Panel (a) >>Ferroptosis_model(40,0,0,0);
Panel (b) >>Ferroptosis_model(40,0,0,2);
Figure 6:
Require: Ferroptosis_model_index.m to run Ferop_index_full.m
>>[Ferrop_Index_Base,Ferrop_Index_Erastin] = Ferrop_index_full(40);
Test varying initial conditions (see Supplementary Information, S1)
If base_var=erastin_var=0, then 1000 different runs of the simulations
with varying initial conditions result in the same steady state
Require: Ferroptosis_model_IC.m to run Ferrop_IC.m
>>[base_var,erastin_var] = Ferrop_IC(1000)
创建时间：
2020-02-29
