Association of Uric Acid Concentrations and hs-CRP (categories, e.g. quartiles) at Baseline With Subsequent Fatal and Non-Fatal CVD Events During Follow-Up.

aconsidered main model - beside the main factors (the variables age, gender and hospital site), the following potential confounders were included in multivariable analyses: smoking status (never, current, ex-smoker), history of myocardial infarction (yes, no), history of diabetes mellitus (yes, no), severity of CHD (number of affected epicardial vessels at baseline), intake of ACE-inhibitors (yes, no), intake of allopurinol (yes, no), HDL-cholesterol (mg/dl), LDL-cholesterol (mg/dl). Only those variables were added to the model which were significant predictors of a subsequent event at a α-level of 0.1 or which changed the parameter estimates for the main variables by more than 10% (details see methods for variable selection).badjusted for above listed variables (a) and CKD-EPI.