A New Organocatalytic Concept for Asymmetric α‑Alkylation of Aldehydes
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https://figshare.com/articles/dataset/A_New_Organocatalytic_Concept_for_Asymmetric_Alkylation_of_Aldehydes/2235835
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资源简介:
The organocatalytic asymmetric α-alkylation
of aldehydes
by 1,6-conjugated addition of enamines to p-quinone
methides is described. Employing a newly developed class of chiral
secondary amine catalysts, α-diarylmethine-substituted aldehydes
with two contiguous stereocenters have been synthesized in a simple
manner with good diastereocontrol and excellent enantioselectivity.
创建时间:
2016-02-16



