Human protein farnesyltransferase complexed with L-778,123 and FPP
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Human protein farnesyltransferase complexed with L-778,123 and FPP Descriptor: 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase beta subunit, ... Authors: Long, S.B, Casey, P.J, Beese, L.S. Deposit date: 2004-01-22 Release date: 2004-07-27 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes. Biochemistry, 43, 2004
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2004-01-22
