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Expression data from LPS/IFNgamma-treated Tet2-/- and Tet2+/+ mouse macrophages.. Mus musculus

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA321440
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We examined the effect of ablation of Tet2, an epigenetic regulator of gene transcription, in the global programme of gene expression underlying pro-inflammatory activation of macrophage. Overall design: Thioglycllate-elicted macrophages were isolated from the Tet2 -/- mice and their wildtype littermates (N=3/group), treated with LPS and IFNg for 10 hours, and isolated for total RNA. Whole-genome transcript profiling was performed using Affymetrix microarray to identify genes that were dysregulated due to Tet2 ablation under the inflammation stimuli.
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2016-05-12
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