Crystal structure of DLK in complex with inhibitor DN0011197
收藏Protein Data Bank Japan2024-04-03 更新2026-04-19 收录
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Crystal structure of DLK in complex with inhibitor DN0011197 Descriptor: Mitogen-activated protein kinase kinase kinase 12, methyl (1S,4S)-5-{(4P)-4-[5-amino-6-(difluoromethoxy)pyrazin-2-yl]-6-[(1R,4R)-2-azabicyclo[2.1.1]hexan-2-yl]pyridin-2-yl}-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate Authors: Srivastava, A, Lexa, K, de Vicente, J. Deposit date: 2022-06-20 Release date: 2022-12-14 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.79 Å) Cite: Discovery of Potent and Selective Dual Leucine Zipper Kinase/Leucine Zipper-Bearing Kinase Inhibitors with Neuroprotective Properties in In Vitro and In Vivo Models of Amyotrophic Lateral Sclerosis. J.Med.Chem., 65, 2022
创建时间：
2022-06-20
