Unconditional, multivariate logistic regression modeling incorporating all detected alleles from sequencing-based classical HLA typing at six loci.

Significant contributions to disease status were established on the basis of a likelihood ratio test of the impact from each allele on the Akaike Information Criterion (P≤0.01). Due to the strong linkage disequilibrium (LD) between DRB1 and DQB1 alleles, and to reduce the degree of freedom of the test, they were modeled as “DRB1-DQB1 blocks” according to LD. aDRB1*13:XX  =  all non-13:01 alleles, i.e. DRB1*13:02, 13:03 and 13:05.
CI: confidence interval, OR: odds ratio
Unconditional, multivariate logistic regression modeling incorporating all detected alleles from sequencing-based classical HLA typing at six loci.