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Total Synthesis of (±)-Rhazinal Using Novel Palladium-Catalyzed Cyclizations

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https://figshare.com/articles/dataset/Total_Synthesis_of_Rhazinal_Using_Novel_Palladium_Catalyzed_Cyclizations/2876782
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A concise synthesis of (±)-rhazinal that hinges on novel oxidative Heck cyclizations and palladium-catalyzed direct couplings is described. An X-ray structure of N-MOM-rhazinal, which provides insight into the conformation of the strained 9-membered lactam ring, is described.
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2009-02-20
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