Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues
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Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues Descriptor: 5-methyl-1,5-dihydro-1,4,5,6,8-pentaazaacenaphthylen-3-amine, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, DIMETHYL SULFOXIDE, ... Authors: Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. Deposit date: 2015-09-22 Release date: 2016-10-05 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2 Å) Cite: A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms. Sci Rep, 6, 2016
创建时间：
2015-09-22
