Role of H4K8ac in P. falciparum life cycle [ChIP]

Study of chromatin changes of P. falciparum in response to changes in the levels of histone H4 acetylations especially H4K8ac using chromatin immunoprecipitation coupled to microarray chip (ChIP-on-chip) ChIP-on-chip of P. falciparum intraerythrocyic life cycle upon hyper or hypo acetylated Histone H4 achieved by treating the cells with HDAC inhibitors or mutating the lysine residues respectively