Genetic signatures of retinal ganglion cells revealed through single cell profiling [non-dissociated RGC]. Genetic signatures of retinal ganglion cells revealed through single cell profiling [non-dissociated RGC]

This study aimed to characterize the transcriptomes of adult retinal ganglion cells (RGCs). The physiological properties of these cells were characterized first in non-dissociated retinal tissue. With that information recorded, the cells were isolated for transcriptome profiling. Overall design: We isolated 29 cells based on their physiological properties and attempted to distinguish them by array profiling.