five

Gene expression of 5-azacytidine-treated HCT116 cells

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE114681
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DNA methylation plays an important role in regulating gene expression. In this study, a subpopulation with accelerated baseline motility (MG cells) or an immotile one (non-MG cells) from a colon cancer cell line (HCT116) were isolated, and gene expression levels of these cells with 5-azacytidine were measured by microarray analysis. Five μM of 5-azacytidine or vehicle was treated into HCT116 cells for 48 hours and then gene expression was measured by human whole-genome microarray (Agilent Technology).
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2019-03-28
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