POSTN secreted from glioblastoma stem cells can recruit microglia and upregulate CD70 expression in microglia through the aVÃ3/PI3K/AKT/NF?B pathway
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https://www.ncbi.nlm.nih.gov/sra/SRP523093
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Our findings revealed that POSTN secreted from GSCs can recruit microglia and upregulate CD70 expression in microglia through the aVÃ3/PI3K/AKT/NF?B pathway, which in turn promotes Treg development and functionality and supports the formation of an immunosuppressive tumor microenvironment. Overall design: Comparative gene expression profiling analysis of RNA-seg data of HMC3 cells treated with PBS or human recombinant POSTN.
创建时间：
2024-10-02
