Genome Methylation Predicts Age and Longevity of Bats

An Infinium microarray platform (GPL28271, HorvathMammalMethylChip40) was used to generate DNA methylation data from several tissues in several bat species. Tissues: skin (wing punches), liver, brain, skeletal muscle. N=860 tissue samples from 28 different bat species were profiled on the mammalian methylation array platform (GPL28271). N=796 of these samples come from wing punches (skin tissue). The remaining samples come from brain (N=9), liver (N=17), muscle (N=17). Due to quality issues N=28 samples were omitted from the analysis, see the characteristic variable CanBeUsedForAgingStudies. We profiled samples from 28 different bat species whose Latin names are as follows: Antrozouspallidus, Artibeusjamaicensis, Carolliaperspicillata, Cynopterusbrachyotis, Desmodusrotundus, Eidolonhelvum, Eptesicusfuscus, Leptonycterisyerbabuenae, Molossusmolossus, Myotisbrandtii, Myotislucifugus, Myotismyotis, Myotisvivesi, Nyctalusnoctula, Nycticeiushumeralis, Phyllostomusdiscolor, Phyllostomushastatus, Pteropusgiganteus, Pteropushypomelanus, Pteropuspoliocephalus, Pteropuspumilus, Pteropusrodricensis, Pteropusvampyrus, Rhinolophusferrumequinum, Rhynchonycterisnaso, Rousettusaegyptiacus, Saccopteryxbilineata, Tadaridabrasiliensis. Gene annotations for the microarray for ten bat genomes are available from the Digital Repository at the University of Maryland (DRUM) at http://hdl.handle.net/1903/26373 . N=48 wing punch samples from different bat species were profiled on the mammalian methylation array platform (GPL28271). We profiled samples from different bat species whose Latin names are as follows: Eptesicus fuscus, Phyllostomus hastatus, Carollia perspicillata. Gene annotations for the microarray for ten bat genomes are available from the Digital Repository at the University of Maryland (DRUM) at http://hdl.handle.net/1903/26373 .