It contains a disruption of the recombination activating gene 2 (RAG2)/pfp and fail to generate mature T or B or NK lymphocytes. (https://www.taconic.com) Gene expression profiling of thymus from Rag2
Total RNA was extracted from the basal epidermis derived from UVB-irradiated P2.5 normal (Mc1r+/Mc1r+; Kit+/Kit+), Mc1r-mutant (Mc1re/Mc1re) and Kit-mutant (Kit/W-v/Kit/W-v) mice. Biological replicate
