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Gene expression profiling of AML cell lines treated with nuclear export inhibitor, selinexor

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE181003
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RNA-seq analysis in OCI-AML2 and MOLM-13 cells treated with selinexor or DMSO for 36 hours. Gene expression profiling was conducted in triplicate and RNA was extracted OCI-AML2 and MOLM-13 cells were treated for 36 hours with vehicle or selinexor (200nM for OCI-AML2 and 75nM for MOLM-13) in biologically independent triplicate. RNA was isolated from whole cells with the RNEasy Mini kit (Qiagen) and sent for paired-end RNA-sequencing by Novogene. Mapped reads were analyzed using DEseq and assessed for differential expression in selinexor versus vehicle-treated conditions.
创建时间:
2023-03-10
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