Cryo-EM structure of HIV-1 reverse transcriptase with a DNA aptamer in complex with rilpivirine
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Cryo-EM structure of HIV-1 reverse transcriptase with a DNA aptamer in complex with rilpivirine Descriptor: 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, DNA (38-MER), Reverse transcriptase/ribonuclease H Authors: Singh, A.K, Das, K. Deposit date: 2022-02-26 Release date: 2022-07-20 Last modified: 2024-07-17 Method: ELECTRON MICROSCOPY (3.38 Å) Cite: Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine. Proc.Natl.Acad.Sci.USA, 119, 2022
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2022-02-26
