Polycomb group (PcG) proteins comprise a large group of evolutionary conserved factors with essential roles for embryonic development and adult stem cell function. PcG proteins constitute two main mul
*χ2-test, P<0.01.Percentage of live pups (%) = No. live pups/No. embryos* 100%; Percentage of herniated pups(%) = No. herniated pups/No. live pups*100%; Co-injection of 2nESCs and 4nESCs into tetraplo
Analysis of SLC35F2 KO hESCs compared with control hESCs. In order to investigate whether SLC35F2 KO affect pluripotency in hESCs, we performed RNA-Seq with SLC35F2 KO and control H9 cells. After esta
NODAL signalling is required to maintain pluripotency in human embryonic stem cells, by maintaining expression of transcription factor NANOG. We treated human blastocysts with NODAL signalling inhibit
