Crystal Structure of Human ADP-ribose Pyrophosphatase NUDT5 In complex with Ibrutinib
收藏Protein Data Bank Japan2024-05-22 更新2026-04-25 收录
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Crystal Structure of Human ADP-ribose Pyrophosphatase NUDT5 In complex with Ibrutinib Descriptor: 1,2-ETHANEDIOL, ADP-sugar pyrophosphatase, Ibrutinib (unbound form), ... Authors: Raux, B, Huber, K.V.M. Deposit date: 2023-12-09 Release date: 2024-05-01 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (2.02 Å) Cite: Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist. J.Med.Chem., 67, 2024
创建时间:
2023-12-09



