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Single cell TCR-RNAseq of thymocyte populations

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NIAID Data Ecosystem2026-05-01 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP357649
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A single cell TCR-RNAseq data set comprised of CD4+CD8+ and CD4+ thymocytes and CD25+ Treg progenitors (TRP), Foxp3lo TRP, de novo developing Tregs and recirculating mature Tregs. Overall design: Pooled thymocytes from 8 female mice (7-12 weeks of age) TCliB+ x TCRa+/- x Foxp3-GFP mice were sorted into 6 populations (CD4+CD8+, CD4+, CD25+ TRP, Foxp3lo TRP, CD73- Treg and CD73+ Treg), each labelled with a specific hashtag. All cells were sorted based on expression of TCR Va2 on the cell surface to reduce TCR diversity.
创建时间:
2023-11-07
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