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Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with an Inhibitory Nanobody (VHH-2g-42)

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with an Inhibitory Nanobody (VHH-2g-42) Descriptor: Plasminogen Activator Inhibitor-1, VHH-2g-42 Authors: Sillen, M, Weeks, S.D, Strelkov, S.V, Declerck, P.J. Deposit date: 2018-06-25 Release date: 2020-01-01 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (2.32 Å) Cite: Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction. J.Thromb.Haemost., 18, 2020
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2018-06-25
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