iPSCORE ATAC-seq: Transcription Factor Binding Predictions

This directory contains three files corresponding to transcription factor binding predictions in ATAC-seq peaks from induced pluripotent stem cells (iPSCs), iPSC-derived cardiovascular progenitor cells (CVPCs), and iPSC-derived pancreatic progenitor cells (PPCs) from the iPSCORE Collection. Transcription factor binding predictions were calculated by TOBIAS (Bentsen et al 2020) using both JASPAR and HOCOMOCO motifs. The files are labeled as [tissue]_JASPAR_HOCOMOCO_Results_.txt. Each file has the following columns: Tissue the corresponding tissue; Peak_ID the identifier for the ATAC-seq peak; Database the motif database (either JASPAR or HOCOMOCO); TFBS_name the name of the motif; Bound whether the binding site was predicted to be bound by TOBIAS; TFBS_Chromsome, TFBS_Start, TFBS_End the genomic coordinates of the binding site in the hg38 build; TFBS_score the score of the binding site calculated by TOBIAS; and TFBS_Strand which strand the binding site is on.

本目录包含对应于诱导多能干细胞（iPSCs）、iPSC来源的心血管祖细胞（CVPCs）和iPSC来源的胰腺祖细胞（PPCs）的ATAC-seq峰转录因子结合预测的三份文件，这些文件均来自iPSCORE Collection。转录因子结合预测通过TOBIAS（Bentsen等人，2020年）计算得出，使用了JASPAR和HOCOMOCO模式。文件标签为[tissue]_JASPAR_HOCOMOCO_Results_.txt。每个文件包含以下列：Tissue，对应组织；Peak_ID，ATAC-seq峰的标识符；Database，模式数据库（JASPAR或HOCOMOCO）；TFBS_name，模式的名称；Bound，TOBIAS预测的结合位点是否被结合；TFBS_Chromsome，TFBS_Start，TFBS_End，结合位点在hg38构建中的基因组坐标；TFBS_score，TOBIAS计算的结合位点得分；TFBS_Strand，结合位点的碱基方向。