Phosphoinositide 3-Kinase gamma bound to an pyrrolopyridinone Inhibitor
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6c1s
下载链接
链接失效反馈官方服务：
资源简介：
Phosphoinositide 3-Kinase gamma bound to an pyrrolopyridinone Inhibitor Descriptor: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, SULFATE ION, {4-[2-(5,6-dimethoxypyridin-3-yl)-5-oxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1H-pyrazol-1-yl}acetonitrile Authors: Jacobs, M.D, Griffin, J.P. Deposit date: 2018-01-05 Release date: 2018-06-27 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Design and Synthesis of a Novel Series of Orally Bioavailable, CNS-Penetrant, Isoform Selective Phosphoinositide 3-Kinase gamma (PI3K gamma ) Inhibitors with Potential for the Treatment of Multiple Sclerosis (MS). J. Med. Chem., 61, 2018
创建时间：
2018-01-05
