Copper(I)-Catalyzed N–O Bond Formation through Vinyl Nitrene Mediated Pathway under Mild Conditions

Copper­(I)-catalyzed N–O bond
formation reactions through
vinyl nitrene-mediated pathway were described. The reactions of N-alkoxylbenzamides and 2H-azirines afforded
α-amino oxime ethers in good to excellent yields at room temperature,
which involved the cleavage of C–N and N–O bonds and
the construction of new N–O and C–N bonds. It offers
an efficient, regio- and stereoselective synthetic route for α-amino
oxime ethers.