Effect of long non-coding RNA LL35/Falcor depletion on gene expression in murine hepatocytes in vivo and in vitro

To determine and compare a functional role of long non-coding RNA LL35/Falcor in murine hepatocytes in vitro and in vivo we performed a transcriptome analysis of AML12 hepatocytes cell line and murine liver after LL35 depletion. Overall design: Differential gene expression profiling analysis of RNA-seq data for AML12 cells with depleted LL35 (AML12 LL35 ASO) in comparison with control (AML12 Luc ASO), and for murine liver (Liver LL35 ASO) in comparison with control (Liver Luc ASO).