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Base-Promoted Synthesis of N‑Substituted 1,2,3-Triazoles via Enaminone–Azide Cycloaddition Involving Regitz Diazo Transfer

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Figshare2016-11-11 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Base-Promoted_Synthesis_of_i_N_i_Substituted_1_2_3-Triazoles_via_Enaminone_Azide_Cycloaddition_Involving_Regitz_Diazo_Transfer/4225469
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The domino reactions between NH-based secondary enaminones and tosyl azide have been developed for the synthesis of various N-substituted 1,2,3-triazoles by employing t-BuONa as the base promoter. Through a key Regitz diazo-transfer process with tosyl azide, the reactions proceed efficiently at room temperature with good substrate tolerance.
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2016-11-11
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