Data accompanying dissertation Miniaturization of PAT - From Concept to Reality

This folder contains data generated during the PhD project: "Miniaturization of Process Analytical Technology: From Concept to Reality"By Mariana Neves Sao Pedro in Delft University of TechnologySupervisors: Marcel Ottens and Michel EppinkDepartment of Biotechnology, Section of Bioprocess Engineering When using the date, please reference <strong>São Pedro et al. (2022)</strong>, Design of a microfluidic mixer channel: First steps into creating a fluorescent dye-based biosensor for mAb aggregate detection (10.1002/biot.202200332); or<strong> </strong><strong style="background-color:rgb(255, 250, 234);">São Pedro et al. (2023)</strong>, Application of a fluorescent dye-based microfluidic sensor for real-time detection of mAb aggregates (10.1002/btpr.3355); or <strong style="background-color:rgb(255, 250, 234);">São Pedro et al. (2023)</strong>, Real-time detection of mAb aggregates in an integrated downstream process (10.1002/bit.28466).

本文件夹收录了玛丽安娜·内维斯·圣佩德罗（Mariana Neves Sao Pedro）在代尔夫特理工大学（Delft University of Technology）开展的博士课题“过程分析技术（Process Analytical Technology, PAT）微型化：从概念到落地”所生成的实验数据。本课题的指导教师为马塞尔·奥滕斯（Marcel Ottens）与米歇尔·埃平克（Michel Eppink），隶属于生物技术系生物过程工程教研室。使用本数据集时，请引用以下文献：1. 圣佩德罗等（2022）：《微流控混合通道设计：开发基于荧光染料的单克隆抗体（monoclonal antibody, mAb）聚集检测生物传感器的初步步骤》，DOI: 10.1002/biot.202200332；2. 圣佩德罗等（2023）：《基于荧光染料的微流控传感器用于单克隆抗体聚集物的实时检测》，DOI: 10.1002/btpr.3355；3. 圣佩德罗等（2023）：《集成下游工艺中单克隆抗体聚集物的实时检测》，DOI: 10.1002/bit.28466。