Project 19.2: Pediatric FN Definition 2012 Bern (NCT01683370): 45 prospectively observed episodes of fever in chemotherapy-induced neutropenia in pediatric patients with cancer

The Pediatric FN Definition 2012 Bern (NCT01683370) study recruited patients from August 2012 to May 2013 in a single Center, the Department of Pediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.39 patients were observed during 289 months of cumulative chemotherapy exposure time. Totally 45 (43+2) episodes of fever in chemotherapy-induced neutropenia (FN) were diagnosed in 20 of the patients.The clinical course of these FN episodes, including >3000 temperature measurements, >300 CBCs, therapy (antipyretics, antibiotics, antifungals, antivirals) and outcomes is described here, together with exact time data. Data are irreversibly anonymized. In order not to compromise anonymization in this small sample of patients, information on gender, age, and malignancy diagnosis is not given.A key-file explains all variables.45 further files contain the data of the single FN episodes.