five

Active transposition in zebrafish.

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PubMed Central1996-10-01 更新2026-05-02 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC38249/
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资源简介:
We have identified a new family of Tc1-like transposons in the zebrafish, Danio rerio. The sequence of a candidate active transposon, deduced from sample Tzf elements, shows limited resemblance to the previously described Tdr1 elements of zebrafish. Both the Tzf and the Tdr elements are extremely abundant in zebrafish. We describe here a general strategy for detecting transposition events in a complex genome and demonstrate its utility by selectively monitoring hundreds of potentially active Tzf copies in the zebrafish genome against a background of other related elements. We have followed members of a zebrafish pedigree, using this two-dimensional transposon display strategy, to identify the first examples of active transposition of such elements in vertebrates. IMAGES:
提供机构:
National Academy of Sciences
创建时间:
1996-10-01
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