Gene expression profiles of mesenterial adipose tissue of newborn rats from dams that were either fed a vitamin D adequate (1,000 IU vitamin D/kg diet) or a vitamin D deficient diet (0 IU vitamin D/kg diet)

The aim of the study was to investigate the role of vitamin D on adipocyte development. To this end, rat dams (Sprague-Dawley rats ) were fed diets with 0 or 1,000 IU vitamin D3 per kg diet 5 weeks prior to conception until the end of lactation. By using high-density DNA microarrays, we analyzed the gene-expression profile of mesenterial adipose tissue of both groups of newborn rats.本研究旨在探究维生素D在脂肪细胞发育过程中的作用。为此，我们选取斯普拉格-道莱（Sprague-Dawley）孕鼠，在受孕前5周至泌乳期结束期间，为其饲喂每千克日粮含0或1000国际单位维生素D3的饲料。本研究采用高密度DNA微阵列（high-density DNA microarrays）技术，对两组新生大鼠的肠系膜脂肪组织基因表达谱进行了分析。