TriosCompass Test Dataset

Here is a drafted description for the dataset to be uploaded to Zenodo. TriosCompass Workflow Test Dataset This dataset provides a complete test case for the TriosCompass workflow, a powerful tool designed for human whole-genome sequencing (WGS) analysis. The dataset is optimized for a quick and comprehensive test run, ensuring the workflow is set up correctly and produces the expected results. Dataset Contents The TriosCompass_test_case.zip archive includes all necessary components to run the test case. Below is a description of the directory structure and files: bam/: Mini-BAM files extracted from the GIAB 40X dataset, covering the genomic region chr17:36,000,000–54,000,000. GIAB_40X.yaml: The configuration file containing parameters required to launch TriosCompass for the GIAB 40X test case. input/: A directory containing the specific input files required by the workflow. launch_40X.sh: A wrapper script designed to submit the TriosCompass Snakemake workflow to a Slurm workload manager. ref/: The hg38 resource bundle/reference files required for TriosCompass execution. TriosCompass_v2/: A clone of the TriosCompass repository (Main branch, commit: 55605b1). expected_output/: A reference directory containing the results generated by a successful run of this test case for validation purposes. Getting Started To use this dataset, simply download and uncompress the TriosCompass_test_case.zip file. The uncompressed directory will contain all the necessary files to launch a test run. You will need to install the required dependencies: Singularity, Conda or Mamba, and the conda environment TriosCompassV2. For detailed instructions on how to install the dependencies and configure the workflow for your computing environment, please refer to the TriosCompass v2 documentation. By running this test case, users can quickly verify their setup and ensure that the workflow is ready for production use.