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Supplementary Material for: Disease-Free Survival for Patients with Thin Melanomas according to the American Joint Committee on Cancer 8th Edition

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DataCite Commons2020-08-27 更新2024-07-27 收录
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https://karger.figshare.com/articles/Supplementary_Material_for_Disease-Free_Survival_for_Patients_with_Thin_Melanomas_according_to_the_American_Joint_Committee_on_Cancer_8th_Edition/8158814/1
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<b><i>Background:</i></b> The recently implemented AJCC 8th edition TNM staging system for malignant melanoma (MM) changed the definition for T1a and T1b tumours. <b><i>Objectives:</i></b> To analyse differences in disease-free survival (DFS) among patients with thin MM staged according to both AJCC 7th and 8th editions. <b><i>Methods:</i></b> An observational study including 285 patients with cutaneous thin MM (thickness ≤1 mm). Cases were staged as T1a and T1b using both 7th and 8th editions. Neither regional nor visceral diseases were present at diagnosis. DFS curves were generated according to the Kaplan-Meier method. <b><i>Results:</i></b> An 8% shift of patients from a T1a towards a T1b stage group was observed after applying the AJCC 8th edition. According to this 8th edition, DFS for T1a patients was significantly longer than for T1b patients (log-rank test; <i>p</i> = 0.005); 5-year DFS for T1a and T1b was 100 and 95%, respectively (Wilcoxon test; <i>p</i> = 0.002). According to the AJCC 7th edition, DFS did not significantly differ for T1a and T1b patients; 5-year DFS for T1a and T1b was 99 and 97%, respectively (<i>p</i> &gt; 0.05). <b><i>Conclusions:</i></b> The AJCC 8th edition seems to be a better tool for staging thin melanomas.
提供机构:
Karger Publishers
创建时间:
2019-05-21
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