Individuals with HLA DR*04 tend to be more impaired but also have lower HIV RNA.

Values (other than sample N) in tables represent averages of the indicated variables. BL is baseline score and 012 is twelve month evaluation point. GDS is ‘global deficit score’ and neurocognitive impairment is defined as ≥0.5. GDS values were square root transformed. Percent ART is percentage of group on at least 2 anti-retroviral medications. CD4 and CD8 value are absolute cells/microliter. HRNA log is log value of HIV RNA copies/ml with a lower limit of detection of 50 copies. All statistical tests are two tailed, values