Spatial Transcriptional Profiling of Pediatric Osteosarcoma Pulmonary Metastases

Dataset contains 9 metastatic osteosarcoma FFPE specimens that were profiled using the Visium CytAssist platform. OS1 - Osteoblastic osteosarcoma, lung parenchyma OS2- Osteoblastic osteosarcoma, lung parenchyma OS3- Osteoblastic osteosarcoma, lung parenchyma OS4- Osteoblastic osteosarcoma, lung parenchyma OS5- Osteoblastic osteosarcoma, lung parenchyma OS6- Chondroblastic osteosarcoma, lung parenchyma OS7- Fibroblastic osteosarcoma, lung parenchyma OS8- Osteoblastic osteosarcoma, hilar lymph node OS9- Osteoblastic osteosarcoma, hilar lymph node RDS files contain Seurat objects that have been preprocessed using SpotClean to correct for spot swapping and filtered to exclude spots with both extremely low and high numbers of counts and features. Seurat objects were normalized using SCTransform.