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Transcriptomic insights into metabolism-dependent biosynthesis of bacterial nanocellulose

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP487551
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Enhancing the productivity through bacterial metabolism engineering is highly sought after but is impeded by our limited knowledge on the BNC synthesis-related metabolic processes. Here, we discovered a metabolism-dependent BNC synthesis processes, which challenges the traditional perception that genome critically determine the biosynthesis behaviors. We compared the transcriptomic profiles of two model BNC-producing strains, Gluconacetobacter hansenii ATCC 53582 and ATCC 23769, which have highly similar genomes but drastically different BNC yields.
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2024-02-03
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