Data for "A hydrolyzed lipid blend diet promotes myelination in neonatal piglets in a region and concentration-dependent manner."

This dataset contains MRI data and Imaris modeling analysis of CLARITY-cleared, immunostained tissue associated with a study that assessed the effects of lipid blends containing various levels of a hydrolyzed fat system on myelin development in healthy neonatal piglets. Data are from thirty-two piglets of mixed sexes across four diet treatment groups and includes a sow-fed reference group. MRI data (presented in Figure 2 of the associated article) consists of volumetric data from Voxel-Based Morphometry analysis in brain grey matter and white matter, as well as mean fractional anisotropy and mean orientation dispersion index data from Tract-Based Spatial Statistics analysis. Imaris data (presented in Figure 3 of the associated article) consists of twenty-one select output measures from 3D modeling analysis of PLP-stained prefrontal cortex tissue. All methods used for collection/generation/processing of data are described in the associated article: Louie AY, Rund LA, Komiyama-Kasai KA, Weisenberger KE, Stanke KL, Larsen RJ, Leyshon BJ, Kuchan MJ, Das T, Steelman AJ. A hydrolyzed lipid blend diet promotes myelination in neonatal piglets in a region and concentration-dependent manner. J Neurosci Res. 2023.

本数据集收录了磁共振成像（MRI）数据及Imaris建模分析，涉及CLARITY技术清除并免疫染色的组织，与一项研究相关联，该研究旨在评估含有不同水平水解脂肪系统的脂质混合物对健康新生仔猪髓鞘发育的影响。数据来源于混合性别的三十二只猪，涵盖四个饮食处理组，并包括母猪喂养的参考组。MRI数据（如图2所示的相关文章）包括基于体素形态计量学分析的脑灰质和白质的体积数据，以及基于轨迹空间统计学的平均各向异性分数和平均方向分散指数数据。Imaris数据（如图3所示的相关文章）包括来自PLP染色前额叶皮层组织三维建模分析的二十一项精选输出指标。所有用于数据收集、生成和处理的手段均在相关文章中进行了描述：Louie AY, Rund LA, Komiyama-Kasai KA, Weisenberger KE, Stanke KL, Larsen RJ, Leyshon BJ, Kuchan MJ, Das T, Steelman AJ. A hydrolyzed lipid blend diet promotes myelination in neonatal piglets in a region and concentration-dependent manner. J Neurosci Res. 2023.