five

Mouse model sequencing for antibody discovery

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1011966
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Sequence data were generated during the characterization of a common light chain mouse model (cLCM), in which the endogenous IGKJ1 to 5 cluster is replaced with a prearranged, modified murine IGKV/IGKJ segment. Antigen positive B-cells from Ovalbumin immunized cLCM and wildtype C56BL/6 mouse were sorted and sequenced using 10x genomics VDJ sequencing workflow.
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2023-09-01
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